Therapeutic liposome comprises bilayer (101) having an internal compartment, where bilayer comprises cis-9,12,15-octadecatrienoic acid, and phospholipid having fatty acid chain of carbon chain length C12 to C24. The cis-9,12,15-octadecatrienoic acid is not attached to the phospholipid, and phospholipid comprises head group and selected from choline, ethanolamine, serine, and inositol. The beta-glucan (103) derived from oat, where beta-glucan is encapsulated into internal compartment having cholesterol (104) and doxorubicin (105).
USE – Therapeutic liposome for treating cancer, which includes ovarian cancer, multiple myeloma, sarcoma, colorectal cancer, and breast cancer (claimed).
ADVANTAGE – The therapeutic liposome improved target cancer, in vivo retention and immune response activation.
Patent Number(s): US9655847-B1