KAIMRC, P.O Box 22490, Riyadh 11426 Saudi Arabia.
+966114294444
+966114294440

Cord Blood Bank

  • Dr. Dunia Jawdat

  • Department
  • About Head
  • Projects
  • Publications
  • Team

King Abdullah International Medical Research Center  Cord Blood Bank (KAIMRC CBB) is a non-profit public cord blood bank. The KAIMRC CBB has been established and authorized to function as a public bank for cord blood units, which can be used to provide treatment for patients who require clinically approved Cellular Therapy (i.e. unrelated use), or for intended families with history of hematological disorders.

Cord blood is the blood that remains in the vein of the umbilical cord and placenta at the time of birth. Recent literature demonstrates that umbilical cord blood is rich in hematopoietic stem cells, which differentiate to all other blood cells and is the foundation of our bodies’ immune system. Cord blood stem cells are already being used to treat nearly 80 diseases, including leukemia, lymphoma, anemia, and inherited metabolic disorders. Over 30,000 transplants have been performed worldwide using stem cells from umbilical cord blood. Since stem cell technologies continue to advance, the opportunities to use preserved cord blood stem cells are steadily increasing.

The KAIMRC CBB is responsible for prospective donor mothers’ recruitment and consent, cord blood collection, processing, testing, cryopreservation, storage, banking, listing, selection and distribution of collected cord blood units.

Cord blood units that do not meet the criteria can be collected and stored for further research purposes to improve the clinical results of such treatment.

As part of our mandate, CBB activities are conducted within a quality system in compliance with national and international standards. On September 15, 2015, KAIMRC CBB received the FACT (Foundation for Accreditation of Cellular Therapy) Accreditation for banking cord blood for both public and intended patient’s family use by demonstrating compliance with the NETCORD-FACT International Standards for Cord Blood Collection, Processing, Testing, Banking, Selection and Release. KAIMRC CBB is the first cord blood bank in the Kingdom and in the Arab world to be recognized and accredited by FACT (http://www.factwebsite.org/Inner.aspx?id=1215&blogid=86&terms=news).

Education

2000-2005 PhD student, Department of Pathology, Faculty of  Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

1998-1999 Internship in Clinical Laboratory Sciences, King Faisal Specialist Hospital and Research Center (KFSH & RC), Riyadh, Saudi Arabia

1993-1998 Bachelor Degree of Applied Medical Sciences, Division of Clinical Laboratory Sciences, King Saud University, Riyadh, Saudi Arabia

Experience

2015  Associate Professor of Immunology, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

2012  Cord Blood Bank, Director, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

2012    Laboratory Consultant in Pathology/ Immunology, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

2010  Research Scientist, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

2009-2015 Assistant Professor of Immunology, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

2009-2010 Associate Research Scientist, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

2005-2006 Postdoctoral Researcher in Immunology, Department of Microbiology and Immunology, Dalhousie University, Halifax, Canada.

Skills & Research Interests

Stem Cell Transplantation

Cord Blood Units

  •  Alrogy W, Jawdat D, Alsemari M, Alharbi A, Alasaad A, Hajeer AH.  Organ Trade Using Social Networks. Saudi J Kidney Dis Transpl. 2016 Sep-Oct;27 (5):971-976
  • Dunia Jawdat. Banking of Human Umbilical Cord Blood. Recent Advances in Stem Cells, From Basic Research to Clinical Applications. Stem Cell Biology and Regenerative Medicine Book. 2016 September; Chapter 8: 159-178.
  • Al-Qahtani R, Al-Hedythi S, Arab S, Aljuhani A, Jawdat D. Factor predicting total nucleated cell counts in cord blood units. 2016
  • Abomaray FM, Al Jumah MA, Alsaad KO, Jawdat D, Al Khaldi A, AlAskar AS, Al Harthy S, Al Subayyil AM, Khatlani T, Alawad AO, Alkushi A, Kalionis B, Abumaree MH. Phenotypic and Functional Characterization of Mesenchymal Stem/Multipotent Stromal Cells from Decidua Basalis of Human Term Placenta. Stem Cells Int. 2016
  • Fakhoury HA, Jawdat D, Alaskar AS, Al Jumah M, Cereb N, Hajeer AH. Three new HLA-C alleles (HLA-C*14:02:13, HLA-C*15:72 and HLA-C*15:74) in Saudi bone marrow donors. Int J Immunogenet. 2015 Oct;42(5):359-60.
  • Abomaray FM, Al Jumah MA, Kalionis B, AlAskar AS, Al Harthy S, Jawdat D, Al Khaldi A, Alkushi A, Knawy BA, Abumaree MH. Human Chorionic Villous Mesenchymal Stem Cells Modify the Functions of Human Dendritic Cells, and Induce an Anti-Inflammatory Phenotype in CD1+ Dendritic Cells. Stem Cell Rev. 2015 Jun;11(3):423-41.
  • Abumaree MH, Al Askar AS, Kalionis B, Abomaray FM, Jawdat D, Hajeer AH, Fakhoury H, Al Jumah MA. Stem cell research and regenerative medicine at king abdullah international medical research center. Stem Cells Dev. 2014 Dec;23 Suppl 1:12-6.
  • Alsultan A, Jarrar M, Mushaqbah W, Al-Sudairy R, Jawdat D. Successful second unrelated cord blood transplantation in a child with juvenile myelomonocytic leukemia. Pediatr Transplant. 2014 Jun 30.
  • Fakhoury HA, Cereb N, JawdatD, Al Jumah M, Alaskar AS, Hajeer AH. Two novel alleles HLA-DRB1*11:150 and HLA-DRB1*14:145 identified in Saudi individuals. Int J Immunogenet. 2014 Jun 12.
  • Fakhoury HA, JawdatD, Alaskar AS, Al Jumah M, Cereb N, Hajeer AH. Two novel alleles HLA-A*02:433 and HLA-A*02:434 identified in Saudi bone marrow donors using sequence-based typing. Int J Immunogenet. 2014 Jun 12.
  • Jawdat D, Arab S, Thahery H, Almeshaqbeh W, Alaskar A and Hajeer H. Improving cord blood units quantity and quality at KAIMRC-Cord Blood Bank. 2014 Jun 9.
  • Jawdat DM, Al Qurashy S, Sayyari A, Marastni M, Ali Hajeer A. Screening panel-reactive antibody negative, single-antigen positive: a case report. Accepted in Progress in Transplantaion 2014 Dec;24(4):341-3.
  • Jawdat D, Sutton P, Al Anazi H, Shubaili A, Al Anazi A, Hajeer A. A Need to Adopting New Strategies for Organ Donation in Saudi Arabia. Prog Transplant. 2014 Sep;24(3):284-7.
  • Jawdatd DM, Al-Jumah M, Al-Hamad B and Hajeer AH. HLA-B50 Polymorphism in the Saudi Population. Int J Immunogenet. 2014 Apr;41(2):95-7.
  • Abumaree MH, Al Jumah MA, Kalionis B, Jawdat D, Al Khaldi A, Abomaray FM, Fatani AS, Chamley LW, Knawy BA. Human Placental Mesenchymal Stem Cells (pMSCs) Play a Role as Immune Suppressive Cells by Shifting Macrophage Differentiation from Inflammatory M1 to Anti-inflammatory M2 Macrophages. Stem Cell Rev. 2013 Oct;9(5):620-41.
  • Abumaree, MA. Al Jumah, B. Kalionis, D. Jawdat, A. Al Khaldi, AA AlTalabani and BA. Knawy. Phenotypic and functional characterization of mesenchymal stem cells from chorionic villi of human term placenta. Stem Cell Rev. 2013 Feb;9(1):16-31
  • Al-Motywee S, Jawdat DM, Jehani GS, Al-Anazi H, Shubaili A, Sutton P, and Hajeer AH. Association of HLA-DRB1*15 and HLA-DQB1*06 alleles with SLE susceptibility in a Saudi population. Ann of Saudi Med. 2013 May-Jun;33(3):229-34.
  • Felimban N, Jawdat DM, Al-Twaijri Y, Al-Mutair A, Tamimi W, Shoukri M, Tamim H and Al-Alwan I. Pubertal characteristics among school girls in Riyadh, Saudi Arabia. Eur J Pediatr. 2013 Jul;172(7):971-5.
  • Al Alwan I, Bin Dajim N, Jawdat DM, Tamimi W, Al Ahmdi R and Al Buhairan F. Prevalence of Auto-Antibodies in Children Newly Diagnosed with Type 1 Diabetes Mellitus. Br J Biomed Sci. 2012;69(1):31-3.
  • Jawdat DM, Al Saleh S, Sutton P, Al Anazi H, Shubaili A, Uyar FA and Hajeer A. HLA-Cw polymorphisms in two Saudi cohorts. Saudi Journal for Kidney Diseases & Transplantation. 2012 Ma; 23: 3. 467-470.
  • Tamimi W, Alassiri M, Alsaeed W,  Alakar A, A Alarifi S, Alenzi F and Jawdat DM, MONOCLONAL GAMMOPATHY IN A TERTIARY REFERRAL HOSPITAL. Clin Biochem. 2010 Jun;43(9):709-13.
  • Dawicki W, Jawdat DM, Xu N, Marshall JS. Mast Cells, Histamine, and IL-6 Regulate the Selective Influx of Dendritic Cell Subsets into an Inflamed Lymph Node. J Immunol. 2010 Feb 15;184(4):2116-23.
  • Jawdat DM, Al Saleh S, Sutton P, Al Anazi H, Shubaili A, Tamim H, Hajeer AH. Chances of finding an HLA-matched sibling: The Saudi experience. Biol Blood Marrow Transplant. 2009 Oct;15(10):1342-4.
  • Jawdat DM, Rowden G, Marshall JS. Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan. J Immunol 2006;177:1755-62.
  • Jawdat DM, Albert EJ, et al. IgE-mediated mast cell activation induces Langerhans cell migration in vivo. J Immunol 2004;173:5275-82
  • Marshall JS, Jawdat DM. Mast cells in innate immunity. J Allergy Clin Immunol 2004;114:21-7.

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