Saudi Stem Cells Donor Registry

  • Dr. Mohsen Alzahrani

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KAIMRC and the National Guard Health Affairs have made history by launching the first Stem Cell Donor Registry in the Arab world. The Stem Cell Registry Program works closely with our Cord Blood Bank and stem cell research remains a top priority for KAIMRC.

In Saudi Arabia, 30% of adult patients and 60% of pediatrics patients cannot find a matching family donor. Therefore, the establishment of the first Saudi Stem Cell Donor Registry for unrelated donors is of utmost need. Stem cell transplantation is used to treat many life-threatening diseases such as Leukemia and Non-Hodgkin’s Lymphoma.

This registry is a KAIMRC national project launched in line with international standards, and is currently in the World Marrow Donor Association (WMDA) accreditation and is already part of the World Wide Bone Marrow Registry.

SSCDR offers another chance for patients who cannot find a family donor, by providing a rich database of potential unrelated donors.

Our life-saving registry plans to recruit 100,000 donors in its first five years through nationwide public awareness campaigns, an ambassador program, marathons, and educational campaigns.

Today, the Kingdom of Saudi Arabia is the first in the Arab world with over 10,000 stem cell donors.

Graduated with a MBChB in November 1999 from King Abdulaziz University, Medical School and finished his Medical Residency at KAMC-R in 2004. He completed his Hematology and Stem Cell Transplant Training at Dalhousie University, Halifax and the University of Toronto, Ontario, Canada from November 2007 to August 2011. Currently, he is the Deputy Chairman of the Oncology Department for quality and safety, Consultant of Hematology and Hematopoietic Stem Cell Transplant, King Abdulaziz Medical City, and also an Assistant Professor in King Saud bin Abdulaziz University for Health Sciences in Riyadh. In addition, Dr. Zahrani has been active in publishing in various research and peer-reviewed journals.

• Fakhoury HA, Alzahrani M, Alaskar AS, Hajeer AH. Description of a novel HLA-DQB1 allele, HLA-DQB1*06:126, in the Saudi stem cell donor registry. HLA. 2016 Jan;87(1):58-9.

• Fakhoury HA1, Jawdat D2, Alaskar AS2, Al Jumah M2, Cereb N3, Hajeer AH. Three new HLA-C alleles (HLA-C*14:02:13, HLA-C*15:72 and HLA-C*15:74) in Saudi bone marrow donors. Int J Immunogenet. 2015 Oct;42(5):359-60.

• Fakhoury HA, Alaskar AS, Hajeer AH. A novel HLA-DQ allele, HLA-DQB1*05:48, found in the Saudi Stem Cells Donor Registry. Tissue Antigens. 2015 Sep;86(3):218-9.

• Fakhoury HA, Cereb N, Jawdat D, Al Jumah M, Alaskar AS, Hajeer AH. Two novel alleles HLA-DRB1*11:150 and HLA-DRB1*14:145 identified in Saudi individuals. Int J Immunogenet. 2014 Aug;41(4):340-1.

• Fakhoury HA, Jawdat D, Alaskar AS, Al Jumah M, Cereb N, Hajeer AH. Two novel alleles HLA-A*02:433 and HLA-A*02:434 identified in Saudi bone marrow donors using sequence-based typing. Int J Immunogenet. 2014 Aug;41(4):338-9.

• Hajeer AH, Al Balwi MA, Aytül Uyar F, Alhaidan Y, Alabdulrahman A, Al Abdulkareem I, Al Jumah M.HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in Saudis using next generation sequencing technique. Tissue Antigens. 2013 Oct;82(4):252-8.

• Hajeer AH, Algattan M, Anizi A, Alaskar AS, Jarrar MS. Chances of finding a matched parent-child in hematopoietic stem cell transplantation in Saudi Arabia. Am J Blood Res. 2012;2(3):201-2.

• Jawdat DM1, Al Saleh S, Sutton P, Al Anazi H, Shubaili A, Tamim H, Hajeer AH. Biol Blood Marrow Transplant. Chances of finding an HLA-matched sibling: The Saudi experience. 2009 Oct;15(10):1342-4.

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