P.O. Box 3660, Riyadh 11481, Mail Code 1515 (KAIMRC)
+966 (11) 429-4444
+966 (11) 429-4440

Colorectal Cancer Research Program

  • Dr. Mohammad Azhar Aziz

  • Department
  • About Head
  • Projects
  • Team

Cancer statistics in Saudi Arabia are growing at an alarming rate. Colorectal cancer tops the list among males. Research that can lead to better prevention, therapy and policy-making will be helpful in decreasing its prevalence and thus the burden on healthcare facilities. It has been achieved in other parts of the world and is feasible in the kingdom as well. Our research focus areas with a vision to address the clinical problems are:

  • Developing Precision/personalized medicine approach
  • Prevention
  • Targeting Metastatic stages

This program aims to generate evidence and data that can be acted upon to improve healthcare for colorectal cancer patients. Eventually there will be products and procedures that can reduce the burden of colorectal cancer.

Our focus on early and accurate diagnosis and prevention will help mitigate the effect of cancer on the Saudi population and contribute to the global efforts in addressing a high incidence cancer. Our research will help advice in formulating national policies on the prevention of colorectal cancers with strong genetic influence. Screening, change in diet and lifestyle, and patient registries based on our research will help reverse the course of increasing incidence in Saudi Arabia.

Dr. Mohammad Azhar Aziz has a long standing interest in cancer research. He has been actively working on colorectal cancer for more than 13 years. Presently, he is leading cancer research efforts at King Abdullah International Medical Research Center (KAIMRC). He is chairman of the board for colorectal cancer research with representatives from different departments and specialties of King Abdul Aziz medical City, King Saud Bin Abdul Aziz University for Health Sciences. His research efforts are focused towards integrative approach to develop novel therapeutic strategies against colorectal cancer. He is developing colorectal cancer research program on three planks of prevention, personalized medicine and treating metastatic stages. He is experienced at developing integrative approach towards cancer therapeutics. He has several projects from intra mural as well as extra mural funding agencies. He has published many research articles in journals of international reputation and authored invited book chapter. Dr. Aziz is also recipient of many awards and honors including European ‘Young Scientist Award’.

Dr. Aziz joined KAIMRC as Associate Research scientist in the year 2010 and was subsequently promoted to research scientist and team leader positions in 2012 and 2015 respectively. Prior to joining KAIMRC, he worked at prestigious hospital associated research institutions – The Cleveland Clinic and Case Western Reserve University, Cleveland, OH, USA. He was also an active member of a National Cancer Institute’s ‘Integrative Cancer Biology Program’ involving many premier institutions across USA. He obtained PhD degree in Biotechnology from one of the best universities in India – Jawaharlal Nehru University, New Delhi.

  • Integrative approach towards designing better therapeutic strategies against cancer
  • Role of Free Fatty Acid Receptors in colorectal cancer
  • Role of ATP8B1 in colorectal Cancer
  • Patient level identification of driver copy number changes integrated with gene expression