Impact Factor:


KAIMRC Affiliation:

No KAIMRC Affiliation – (AlMallah – KACC KAMC)

Name of Article:

Response to Comment on Juraschek et al. Cardiorespiratory Fitness and Incident Diabetes: The FIT (Henry Ford ExercIse Testing) Project.


Juraschek, S., Blaha, M., and Al-Mallah, M.


Diabetes Care

Year of Publication:


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The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD; Henry Ford Hospital, Detroit, MI, and Cardiac Imaging, King Abdulaziz Cardiac Center, Ministry of National Guard–Health Affairs, Riyadh, Kingdom of Saudi Arabia



Along with obesity, fitness is a strong risk factor for diabetes in multiple cohort studies (2–4). However, the extent to which obesity serves as a confounder of this relationship is unclear. Our study shows that fitness is associated with incident diabetes independent of an incomplete measure of obesity, ascertained via self-report and medical records (5). However, even after accounting for BMI, available in medical records of 11,750 patients, the relationship between fitness and incident diabetes remained strong. While obesity may to some extent confound the relationship between fitness and incident diabetes (see Supplementary Table 3 in ref. 5), it does not fully account for this association, an important conclusion of our article.